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美国内科年鉴发表中国临床试验报告表明针灸治疗慢性便秘有效

2016-9-14 09:41| 发布者: 心之水选择| 查看: 33| 评论: 0

摘要: 核心提示:在美国业界具有很高影响力的美国《内科医学年鉴》,于2016年9月13日在线发表了一篇中国学者的针灸治疗慢性严重功能性便秘的临床试验报告,表明针灸治疗慢性便秘有效。   世界中医药网讯(本网特邀记者李 ...
核心提示:在美国业界具有很高影响力的美国《内科医学年鉴》,于2016年9月13日在线发表了一篇中国学者的针灸治疗慢性严重功能性便秘的临床试验报告,表明针灸治疗慢性便秘有效。

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  世界中医药网讯(本网特邀记者李永明美国报道)在美国业界具有很高影响力的美国《内科医学年鉴》,于2016年9月13日在线发表了一篇中国学者的针灸治疗慢性严重功能性便秘的临床试验报告,表明针灸治疗慢性便秘有效。

  该项针灸试验有15个医院参加,共纳入千余患者。半数接受腹部传统穴位电针治疗,半数接受非穴位浅刺假电针治疗。疗程8周28次,观察20周。观察指标为毎周排便次数,属于随机单盲对照多中心试验研究。结果表明,接受真针灸治疗的患者比接受假针灸治疗的患者的排便次数增加大约一倍多,多数达到正常,无明显副作用,统计结果有非常显著性差异。

  该项研究由中国中医科学院刘保延研究员领衔,包括20多位作者,研究团队阵容强大。是中国内陆学者首次在此类高信誉国际学刊发表针灸试验报告,意义重大。该项试验的特点是大样本、多中心,为中国国家十二五科技支撑计划项目。

  其实,针灸能促进胃肠蠕动是针灸界人人皆知的事实,治疗动物也屡试不爽。1971年纽约时报记者赖斯顿在北京因阑尾炎术后接受针灸治疗,就是为了促进术后胃肠蠕动。他曾在纽约时报发表文章说针灸有效,可惜医学界不承认个案为证据。事隔45年,中国学者终于拿出了大样本数据,证明赖斯顿没有“撒谎”。医学临床研究之严谨和艰难,由此可见一斑。

下面是原文摘要和链接:

Acupuncture for Chronic Constipation

Ann Intern Med. 13 September 2016

Published>Objective: To determine the efficacy of electroacupuncture (EA) for chronic severe functional constipation (CSFC).

Setting: 15 hospitals in China.

Participants: Patients with CSFC and no serious underlying pathologic cause for constipation.

Intervention: 28 sessions of EA at traditional acupoints or sham EA (SA) at nonacupoints over 8 weeks.

Measurements: The primary outcome was the change from baseline in mean weekly complete spontaneous bowel movements (CSBMs) during weeks 1 to 8. Participants were followed until week 20.

Results: 1075 patients (536 and 539 in the EA and SA groups, respectively) were enrolled. The increase from baseline in mean weekly CSBMs during weeks 1 to 8 was 1.76 (95% CI, 1.61 to 1.89) in the EA group and 0.87 (CI, 0.73 to 0.97) in the SA group (between-group difference, 0.90 [CI, 0.74 to 1.10]; P < 0.001). The change from baseline in mean weekly CSBMs during weeks 9 to 20 was 1.96 (CI, 1.78 to 2.11) in the EA group and 0.89 (CI, 0.69 to 0.95) in the SA group (between-group difference, 1.09 [CI, 0.94 to 1.31]; P < 0.001). The proportion of patients having 3 or more mean weekly CSBMs in the EA group was 31.3% and 37.7% over the treatment and follow-up periods, respectively, compared with 12.1% and 14.1% in the SA group (P <0.001). Acupuncture-related adverse events during treatment were infrequent in both groups, and all were mild or transient.

Limitations: Longer-term follow-up was not assessed. Acupuncturists could not be blinded.

Conclusion: Eight weeks of EA increases CSBMs and is safe for the treatment of CSFC. Additional study is warranted to evaluate a longer-term treatment and follow-up.

http://annals.org/article.aspx?articleid=2552074